Work Package 3

GENERATION OF RELEVANT ANIMAL MODELS OF CSDs AND RSDs

 

Work package leaders:

Stephan Sonntag (POLYGENE) and Raymund Wagener (UKK)

 

Objectives:

  • To develop relevant in vivo models of RSDs and CSDs.
  • To evaluate and apply TALEN technology for the generation of genetically modified zebrafish and mice.
  • To develop, apply and evaluate rE-Rex for the reversible switch on/off of gene expression in vivo.

 

Partners ivolved in WP3: